Modulation of blood pressure by dietary potassium and sodium: sex differences and modeling analysis
This computational modeling study, based on rat data and extrapolated to humans, suggests that sex-specific differences in renal transporter abundance may contribute to women's attenuated blood pressure response to hypertensive stimuli, including high sodium intake. The model also predicts that high potassium intake can lower blood pressure, even in the presence of high sodium, but the magnitude of the effect differs between sexes due to variations in baseline renal sodium handling.
stadt-layton-2025-modulation-of-blood-pressure-by-dietary-potassium-and-sodium-sex-differences-and-modeling-analysis.pdf
