Frequency and clinical characteristics of kidney involvement in children with suspected COVID-19 infection: a single-center cross-sectional study
Overview
Paper Summary
This single-center cross-sectional study found that 18.3% of hospitalized children with suspected or confirmed COVID-19 developed acute kidney injury (AKI). AKI was associated with more severe disease, gastrointestinal symptoms, and lab abnormalities like low platelets, high CRP, hypocalcemia, and hyperphosphatemia.
Explain Like I'm Five
In this study, some kids hospitalized with suspected COVID-19 also had kidney problems. Kids with kidney issues were sicker overall and had some tell-tale blood test changes.
Possible Conflicts of Interest
None identified
Identified Limitations
Rating Explanation
This study provides valuable descriptive data on AKI in hospitalized children with suspected COVID-19. However, the cross-sectional design, lack of baseline data, and short follow-up limit the ability to draw strong conclusions about causality or prognosis. The single-center nature also restricts generalizability. Overall, it's an average study with important limitations.
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