Browse research papers in Virology - Immunology and Microbiology Discover 4 academic papers with AI-powered analysis

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Virology

The study of viruses and viral diseases, including viral structure, replication, pathogenesis, evolution, antiviral drugs, viral vectors, and emerging viral threats to human and animal health

4 papers in this specialization

Papers

Metabolic reprogramming in viral infections: the interplay of glucose metabolism and immune responses

This review discusses the multifaceted role of glucose metabolism in viral infections, exploring how it supports both immune activation and viral replication. The interplay between immune responses, metabolic reprogramming, and various viral subtypes is highlighted, along with potential therapeutic opportunities for antiviral development.

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Metabolic_reprogramming_in_viral_infections_the_in.pdf

Aug 01, 08:33 AM

Phylogenomic characterization and signs of microevolution in the 2022 multi-country outbreak of monkeypox virus

The 2022 monkeypox outbreak likely originated from a single source and belongs to clade 3. The virus exhibits accelerated evolution, potentially driven by APOBEC3-mediated genome editing, and shows signs of ongoing microevolution during human-to-human transmission.

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s41591-022-01907-y.pdf

Jul 14, 10:51 AM

Role of Oral Rabies Vaccines in the Elimination of Dog-Mediated Human Rabies Deaths

This review discusses the potential of oral rabies vaccines (ORV) for dogs as a crucial tool to eliminate dog-mediated human rabies deaths, especially in resource-limited settings where traditional parenteral vaccination faces challenges. While acknowledging safety concerns and regulatory obstacles, the authors argue for the integration of ORV into vaccination campaigns, emphasizing their cost-effectiveness and ability to reach inaccessible dog populations.

Elimination of human rabies in Goa, India through an integrated One Health approach

This study reports the successful elimination of human rabies deaths in Goa, India, through a six-year One Health program (2013-2019). The program combined mass dog vaccination, rabies education, and enhanced surveillance, leading to a 92% reduction in canine rabies cases and zero human rabies deaths in 2018 and 2019. The intervention was deemed "very cost-effective" by WHO standards.

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s41467-022-30371-y.pdf

Jul 14, 10:51 AM