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Medicine
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Oncology
Oncology
Cancer diagnosis and treatment, including medical oncology, radiation oncology, surgical oncology, cancer immunotherapy, precision oncology, and palliative care
2 papers in this specialization
Papers
Metal complexes as a promising source for new antibiotics
This study investigated the antimicrobial activity of 906 metal-containing compounds and found a significantly higher hit-rate (9.9% non-toxic) compared to purely organic molecules (0.87%). Out of these, 30 non-toxic compounds displayed promising activity against various bacterial and fungal strains, highlighting the potential of metal complexes as a source for new antibiotics.
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c9sc06460e.pdf
Jul 14, 10:39 AM
Targeting of radioactive platinum-bisphosphonate anticancer drugs to bone of high metabolic activity
Researchers developed a radioactive platinum-bisphosphonate complex (195mPt-BP) that selectively targets bone with high metabolic activity, showing potential for treating bone metastases. The compound accumulated in the bone tissue of mice with minimal off-target effects and slow release of platinum, suggesting a safer and more effective therapeutic strategy.
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s41598-020-62039-2.pdf
Jul 14, 10:39 AM
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