Supplementary Data on Gene Expression and Tumor Characteristics in Oral Cancer

Overview

Paper Summary › Explain Like I'm Five › Conflicts of Interest › Identified Limitations › Rating Explanation › Good to know › Topic Hierarchy › File Information ›

Paper Summary

Paperzilla title

This supplementary information provides additional data tables for a study on oral cancer, including gene expression profiles, tumor-initiating cell frequencies, and the effects of a CD36 antibody. The data details gene expression differences in various cell populations, glucose levels and weight in mice fed different diets, metastasis-initiating cell frequencies, and blood parameters measured in treated and untreated mice.

Explain Like I'm Five

This extra information for a cancer study shows which genes are more or less active in different cancer cells and how a potential treatment affects tumor growth and other factors in mice.

Possible Conflicts of Interest

None identified

Identified Limitations

Lack of Standalone Information

This supplementary material does not provide sufficient context or independent conclusions without the main article. It is impossible to determine the methodology's soundness or the significance of the findings without the primary publication.

Limited Interpretation

The tables provide data points, but offer minimal explanation or interpretation of their significance. It's hard to gauge the impact of the observed differences without further analysis.

Reliance on Mouse Models

Some data comes from mouse models, which limits the direct applicability of the findings to humans. The supplementary material does not address the limitations of mouse models in relation to human oral cancer.

Rating Explanation

This supplementary information provides valuable data for the main study but is impossible to evaluate independently. It is dependent on the primary publication for context and conclusions. The use of mouse models limits human relevance, justifying a rating of 3.

Good to know

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Topic Hierarchy

Domain: Health Sciences

Field: Medicine

Subfield: Oncology

File Information

Original Title: SUPPLEMENTARY INFORMATION

Uploaded: September 21, 2025 at 11:38 AM

Privacy: Public