Companion animal medicine, including dogs, cats, and exotic pets, covering internal medicine, surgery, behavior, nutrition, and preventive care for household pets
3 papersThis paper explains and elaborates on the updated ARRIVE 2.0 guidelines for reporting animal research. It provides detailed guidance on each of the 21 items, categorized as "Essential 10" and "Recommended Set," aiming to enhance transparency, reproducibility, and ultimately improve preclinical research standards.
The ARRIVE 2.0 guidelines are an updated version of the ARRIVE guidelines designed to improve the reporting of animal research. The key changes include a revised checklist of 21 items divided into two sets: the "Essential 10" and the "Recommended Set", along with an explanation and elaboration document to facilitate implementation and promote better transparency and reproducibility.
Researchers created a chromosome-level genome assembly for the barber pole worm (H. contortus), a parasite of sheep and goats. This revealed a surprising lack of gene order conservation with the model nematode C. elegans despite similar chromosome content, high genetic diversity within the parasite, and extensive gene splicing that contributes to transcriptome complexity.