Paper Summary
Paperzilla title
ARRIVE 2.0: Level Up Your Animal Research Reporting!
The ARRIVE 2.0 guidelines are an updated version of the ARRIVE guidelines designed to improve the reporting of animal research. The key changes include a revised checklist of 21 items divided into two sets: the "Essential 10" and the "Recommended Set", along with an explanation and elaboration document to facilitate implementation and promote better transparency and reproducibility.
Possible Conflicts of Interest
Some authors are employed by or have received funding from the NC3Rs, which supported this work. Other authors have declared various competing interests, including roles in other journals, funding from other organizations, and shareholdings in pharmaceutical companies.
Identified Weaknesses
Reliance on Delphi exercise
The study relies heavily on a Delphi exercise, which, while useful for gathering expert opinions, can be susceptible to biases and may not fully represent the broader scientific community.
Limited road testing sample
The road testing phase involved a small number of researchers, limiting the generalizability of the findings regarding the usability and understanding of the revised guidelines.
Implementation challenges
While ARRIVE 2.0 provides more detailed guidance, its effectiveness relies heavily on the active involvement of journal staff and editors, which can be a significant challenge in practice.
Rating Explanation
The ARRIVE 2.0 guidelines represent a significant improvement in reporting standards for animal research, addressing key limitations of the previous version and promoting greater transparency and reproducibility. While the implementation of the guidelines faces practical challenges and the long-term impact remains to be seen, the rigorous methodology used in their development warrants a strong rating.
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File Information
Original Title:
The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research
Uploaded:
July 14, 2025 at 11:19 AM
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