Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0
Overview
Paper Summary
This paper explains and elaborates on the updated ARRIVE 2.0 guidelines for reporting animal research. It provides detailed guidance on each of the 21 items, categorized as "Essential 10" and "Recommended Set," aiming to enhance transparency, reproducibility, and ultimately improve preclinical research standards.
Explain Like I'm Five
Scientists made a checklist to help researchers tell everyone exactly what they did when they study animals. This helps make sure animal studies are clear and that other scientists can learn from them.
Possible Conflicts of Interest
Some authors are employed by or affiliated with organizations that promote animal welfare and the 3Rs (Replacement, Refinement, and Reduction of Animals in Research), which could be perceived as a potential conflict of interest.
Identified Limitations
Rating Explanation
This explanation and elaboration document for ARRIVE 2.0 is an essential resource for improving the reporting quality of animal research. It offers detailed explanations, rationale, and examples for each of the 21 ARRIVE items, supporting researchers in enhancing transparency and reproducibility. While it acknowledges some potential challenges in implementing all guidelines, the overall message promotes rigorous and ethical animal research. The potential conflict of interest is noted but does not significantly detract from the document's value.
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