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Health Sciences › Veterinary › Small Animals
Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0
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Conflicts of Interest
Identified Weaknesses
Rating Explanation
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Paper Summary
Paperzilla title
ARRIVE 2.0: A Reporting Checklist for Animal Research - Because Transparency Matters!
This paper explains and elaborates on the updated ARRIVE 2.0 guidelines for reporting animal research. It provides detailed guidance on each of the 21 items, categorized as "Essential 10" and "Recommended Set," aiming to enhance transparency, reproducibility, and ultimately improve preclinical research standards.
Possible Conflicts of Interest
Some authors are employed by or affiliated with organizations that promote animal welfare and the 3Rs (Replacement, Refinement, and Reduction of Animals in Research), which could be perceived as a potential conflict of interest.
Identified Weaknesses
Limited empirical evidence
It would be beneficial to see more empirical evidence supporting the claims made in systematic reviews, especially when it comes to animal research, as individual studies might not always provide a complete or unbiased picture.
Potential challenges in following ARRIVE guidelines strictly
While the ARRIVE guidelines provide a good framework for reporting animal research, there could be instances where strict adherence to all guidelines isn't feasible due to the specifics of the study, but a rationale for this deviation should be provided.
Incomplete reporting of animal characteristics
Clear and detailed descriptions are key to reproducibility. Explicitly mentioning when certain information like weight or sex of animals isn't reported, along with the reasons, helps in maintaining transparency.
Lack of transparency regarding ethical approvals
This promotes transparency and accountability in research and reassures readers and reviewers that ethical considerations have been met.
Rating Explanation
This explanation and elaboration document for ARRIVE 2.0 is an essential resource for improving the reporting quality of animal research. It offers detailed explanations, rationale, and examples for each of the 21 ARRIVE items, supporting researchers in enhancing transparency and reproducibility. While it acknowledges some potential challenges in implementing all guidelines, the overall message promotes rigorous and ethical animal research. The potential conflict of interest is noted but does not significantly detract from the document's value.
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File Information
Original Title:
Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0
File Name:
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July 14, 2025 at 11:19 AM
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