Browse research papers in Physiology - Biochemistry, Genetics and Molecular Biology Discover 2 academic papers with AI-powered analysis

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Biochemistry, Genetics and Molecular Biology

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Physiology

The study of how organisms function at all levels, from molecules to organ systems, including cardiovascular, respiratory, neural, renal, and digestive physiology, homeostasis, and adaptation to environmental challenges

2 papers in this specialization

Papers

Rescue of germ cells in dnd crispant embryos opens the possibility to produce inherited sterility in Atlantic salmon

This study rescued germ cells in genetically modified sterile Atlantic salmon by co-injecting wild-type dnd mRNA with CRISPR-Cas9 constructs targeting the dnd gene. Rescued one-year-old fish contained germ cells in their gonads, despite high dnd mutation rates, suggesting a potential pathway for large-scale production of sterile salmon offspring through genetically sterile broodstock.

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s41598-020-74876-2.pdf

Jul 14, 11:25 AM

Elevated protein synthesis in microglia causes autism-like synaptic and behavioral aberrations

Overexpression of the protein synthesis initiation factor eIF4E in microglia, but not neurons or astrocytes, leads to autism-like behaviors in male mice. This effect is sex-specific, with male mice showing increased microglial density and size, altered synaptic function, and social deficits, while female mice remain largely unaffected.

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s41467-020-15530-3.pdf

Jul 14, 11:25 AM