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Pharmacology, Toxicology and Pharmaceutics
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Pharmaceutical Science
Pharmaceutical Science
Drug formulation and delivery, including pharmaceutics, pharmacokinetics, drug stability, controlled release systems, and the development of novel drug delivery technologies
3 papers in this specialization
Papers
Nanoparticle-based drug delivery systems for cancer therapy
Nanoparticle-based drug delivery systems offer improved efficacy for cancer treatment compared to traditional methods by enhancing drug half-life, solubility, and targeted release. This review focuses on chitosan, silica, and PLGA nanoparticles, detailing their fabrication and applications while acknowledging current limitations and future research needs.
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pmc8455119.pdf
Jul 14, 10:54 AM
Microneedle array delivered recombinant coronavirus vaccines: Immunogenicity and rapid translational development
This study demonstrates the rapid development and immunogenicity of a novel microneedle array (MNA) delivered recombinant SARS-CoV-2 vaccine. The MNA-delivered vaccine elicited potent and long-lasting antigen-specific antibody responses in mice, suggesting a promising new approach for coronavirus vaccination.
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pmc7128973.pdf
Jul 14, 10:54 AM
Formulation and evaluation of cyclodextrin-based nanosponges of griseofulvin as pediatric oral liquid dosage form for enhancing bioavailability and masking bitter taste
This study developed a cyclodextrin-based nanosponge formulation of griseofulvin that significantly improved drug dissolution, enhanced bioavailability in rats, and effectively masked the bitter taste in a human panel. This approach offers a potential solution for pediatric oral liquid formulations of griseofulvin.
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pmc7078523.pdf
Jul 14, 10:54 AM
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