Browse research papers in Endocrine and Autonomic Systems - Neuroscience Discover 4 academic papers with AI-powered analysis

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Endocrine and Autonomic Systems

Neuroendocrine regulation and autonomic function, including stress responses, circadian rhythms, autonomic disorders, and the interaction between the nervous and endocrine systems

4 papers in this specialization

Papers

Monosynaptic Projections to Excitatory and Inhibitory preBötzinger Complex Neurons

This study identified the brainstem and suprapontine regions that directly project to excitatory and inhibitory neurons in the preBötzinger Complex (preBötC), the breathing rhythm generator. Surprisingly, both neuron types receive input from the same brain areas involved in various functions including breathing, emotion, and motor control, implying that the balance of these inputs, rather than separate pathways, may fine-tune breathing.

Opioids depress breathing through two small brainstem sites

This study identified two small areas in the mouse brainstem, the preBötzinger Complex (preBötC) and the parabrachial/Kölliker-Fuse nuclei (PBN/KF), as critical for opioid-induced respiratory depression (OIRD). Within the preBötC, a small subset of approximately 140 glutamatergic neurons were found to mediate this effect in vitro.

Sleep cycle-dependent vascular dynamics in male mice and the predicted effects on perivascular cerebrospinal fluid flow and solute transport

This study found that blood vessels in the brains of male mice display distinct dynamics across different sleep stages, with slow vasomotion during NREM sleep, dilation during REM sleep, and constriction upon awakening. Biomechanical modeling suggests these dynamics likely enhance cerebrospinal fluid flow and solute transport in the perivascular spaces, particularly during NREM sleep, with potential implications for brain waste clearance.

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s41467-023-36643-5.pdf

Jul 14, 11:16 AM

Recommendations for daytime, evening, and nighttime indoor light exposure to best support physiology, sleep, and wakefulness in healthy adults

The study recommends a minimum daytime melanopic EDI of 250 lux, a maximum evening melanopic EDI of 10 lux starting 3 hours before bed, and a maximum nighttime melanopic EDI of 1 lux for optimal sleep and wakefulness. These recommendations are based on melanopsin's influence on non-visual light responses and are intended to promote healthy circadian rhythms and improve alertness, sleep, and mood.