Surgical treatment of disease and injury, including general surgery, minimally invasive surgery, robotic surgery, transplant surgery, surgical oncology, and perioperative care
6 papersIn a multi-center study, using Glubran 2, a surgical glue, to reinforce colon connections after surgery, the rate of leaks decreased significantly. While the results are positive, the lack of a control group makes it hard to definitively say the glue is the only reason for the improvement. Further research with control groups is needed to strengthen the findings.
This paper describes a new "duodenal-window-first" approach to pancreatic surgery (pancreatoduodenectomy). The authors present a case series of 15 patients who underwent this procedure and report no specific complications, although one patient died of unrelated causes post-operatively. Further clinical studies with a larger sample size are needed to validate the technique and compare it to existing methods.
This review summarizes the therapeutic potential of stem cell-derived exosomes in various surgical fields, highlighting their advantages over traditional stem cell therapy and their mechanism of action through tissue-specific responses and cellular signaling pathways. It also discusses the production, modification, characterization, and storage of exosomes, emphasizing their potential as a safe and versatile alternative for managing surgical conditions.
BMSC-Exos injections improved rotator cuff healing in rats by boosting blood vessel formation around the injury and calming down inflammation. This led to stronger repairs and better joint function after surgery, suggesting a potential new treatment for rotator cuff tears.
Peripheral nerve injuries in the upper extremity lead to significant costs, long sick leave, and often permanent disability, with 30% receiving disability pensions. The average cost for an injured individual over their lifetime could reach €102,167, emphasizing the substantial socioeconomic burden of these injuries, especially in work-related accidents.
Distal radius fractures (DRFs) predominantly affect elderly women (≥50 years) due to low-energy simple falls, often occurring at home. Most DRFs are extra-articular and treated non-surgically, but surgical treatment is increasing, especially for intra-articular fractures, with plate fixation being the most common method.