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Medicine
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Rehabilitation
Rehabilitation
Restoration of function after illness or injury, including physical medicine, occupational therapy, speech therapy, cardiac rehabilitation, and assistive technology
3 papers in this specialization
Papers
TRPV1 alleviates osteoarthritis by inhibiting M1 macrophage polarization via Ca²+/CaMKII/Nrf2 signaling pathway
This study found that TRPV1, a receptor activated by capsaicin (the compound that makes chili peppers spicy), can reduce inflammation in joints affected by osteoarthritis. Activating TRPV1 inhibits the activity of M1 macrophages, which drive inflammation and joint damage, and promotes cartilage health in a rat model.
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s41419-021-03792-8.pdf
Jul 14, 10:56 AM
An image J plugin for the high throughput image analysis of in vitro scratch wound healing assays
This paper introduces a new ImageJ/Fiji plugin, 'Wound Healing Size Tool', for analyzing in vitro scratch wound healing assays. This plugin aims to automate the process of quantifying wound area, coverage, average width, and width standard deviation, allowing for high-throughput analysis of scratch assays. Testing shows that conditioned media from hAdMSCs promotes faster wound closure and higher cell migration rates in HaCaT cells compared to control media.
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file.pdf
Jul 14, 10:56 AM
Re-epithelialization and immune cell behaviour in an ex vivo human skin model
This study established a novel ex vivo human skin wound model using suction blisters, mimicking the regenerative process of wound healing. The model showed successful re-epithelialization and differentiation of epidermal cells, suggesting its potential for testing wound healing therapies.
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s41598-019-56847-4.pdf
Jul 14, 10:56 AM
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