A single bout of resistance or high-intensity interval training increases anti-cancer myokines and suppresses cancer cell growth in vitro in survivors of breast cancer
Overview
Paper Summary
This study examined how a single session of either resistance training (RT) or high-intensity interval training (HIIT) affected anti-cancer molecules (myokines) and breast cancer cell growth in a lab setting using blood samples from breast cancer survivors. Both RT and HIIT increased myokine levels and reduced cancer cell growth in the lab, with HIIT showing slightly stronger effects on cell growth immediately after exercise.
Explain Like I'm Five
A single workout, whether lifting weights or doing intense intervals, can boost your body's natural cancer-fighting molecules and slow down breast cancer cell growth in a lab dish.
Possible Conflicts of Interest
None identified
Identified Limitations
Rating Explanation
This is a pilot study with a decent sample size and randomized design, providing preliminary insights into the acute effects of exercise on myokines and cancer cell growth in breast cancer survivors. However, the in vitro nature of the study, its limited scope to a single exercise bout, and use of only one cancer cell line significantly limit the generalizability of the findings. Thus, a rating of 3 is appropriate.
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