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Biomaterials

Materials for medical and biological applications, including implants, tissue engineering scaffolds, drug delivery systems, biocompatibility, and the interaction between materials and biological systems

3 papers in this specialization

Paperzilla Papers in Biomaterials

Bio-inspired geotechnical engineering: principles, current work, opportunities and challenges

This review explores how biological mechanisms used by organisms like worms, ants, and tree roots for interacting with soil can inspire innovative solutions in geotechnical engineering. It highlights ongoing research in areas such as soil penetration, anchorage, and thermal transport, emphasizing the potential benefits while acknowledging the challenges of scaling up these natural strategies for practical applications.

Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines

This study developed macrophage membrane-coated, ROS-responsive nanoparticles for targeted drug delivery and cytokine sequestration to treat atherosclerosis. The nanoparticles successfully targeted atherosclerotic plaques in mice, released the drug atorvastatin in response to ROS, and sequestered proinflammatory cytokines, leading to a significant reduction in plaque area and inflammation compared to free drug or macrophage-internalized nanoparticles.

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s41467-020-16439-7.pdf

Jul 14, 10:45 AM

Recent advance in surface modification for regulating cell adhesion and behaviors

This review explores how modifying the surface of materials can control how cells stick to them (cell adhesion). It covers factors influencing cell adhesion, like surface roughness and wettability, and discusses different modification methods, from self-assembled monolayers to 3D bioprinting, using materials like silicon and polymers.