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Analytical Chemistry

The development and application of methods to identify and quantify matter, including spectroscopy, chromatography, mass spectrometry, electroanalytical techniques, and chemical sensors for various applications

3 papers

Papers

MIPs for commercial application in low-cost sensors and assays - An overview of the current status quo

Molecularly imprinted polymers (MIPs) offer a promising, low-cost alternative to bioreceptors in sensors and assays, boasting robust stability and straightforward synthesis. Despite their potential, widespread commercialization of MIP-based systems has been hampered by challenges in mass production and integration into user-friendly devices, but recent advances in commercial MIP synthesis and assay development are paving the way for broader adoption in various fields, including diagnostics, environmental monitoring, and food safety.

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Analytical Chemistry Jul 14, 2025, 10:50:09 AM

Management of validation of HPLC method for determination of acetylsalicylic acid impurities in a new pharmaceutical product

The study validated an HPLC method for determining impurities in acetylsalicylic acid-glycine tablets, confirming its linearity, accuracy, and precision within the tested range (0.005-0.40% salicylic acid). Forced degradation studies showed that the method can effectively separate the active ingredients and salicylic acid from degradation products.

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Analytical Chemistry Jul 14, 2025, 10:49:56 AM