Browse research papers in Cell Biology - Biochemistry, Genetics and Molecular Biology Discover 4 academic papers with AI-powered analysis

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Biochemistry, Genetics and Molecular Biology

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Cell Biology

The study of cell structure, function, and behavior, including organelles, cell division, signaling, metabolism, differentiation, and the molecular mechanisms governing cellular processes in health and disease

4 papers in this specialization

Papers

ROS transfer at peroxisome-mitochondria contact regulates mitochondrial redox

This study demonstrates that peroxisomes play a direct role in maintaining mitochondrial health by acting as sinks for mitochondrial reactive oxygen species (ROS) through a contact site mediated by proteins ACBD5 and PTPIP51. The study was conducted using immortalized cell lines and further research is needed to confirm these findings in vivo. This contact increases during mitochondrial oxidative stress, helping to maintain mitochondrial function by transferring excess ROS from the mitochondria to the peroxisome lumen.

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DiGiovanni et al. - 2025 - ROS transfer at peroxisome-mitochondria contact regulates mitochondrial redox.pdf

Jul 19, 04:22 PM

A proximity-dependent biotinylation map of a human cell

Researchers created a detailed map of protein locations within a human cell using a proximity-based labeling technique. They identified over 4,000 proteins across 20 different cellular compartments and discovered new proteins important for mitochondrial health, showcasing the power of their new online resource, humancellmap.org.

Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9

This study demonstrates that in HeLa cells, small ectosomes (EVs budding directly from the plasma membrane) are more prominent than exosomes (EVs formed within endosomes). They identify new protein markers to distinguish these two EV populations and show that the endosomal pH affects exosome secretion but not ectosome secretion, confirming their different origins.

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s41467-021-24384-2.pdf

Jul 14, 05:08 PM

Natural skin-whitening compounds for the treatment of melanogenesis (Review)

This review explores natural compounds that interfere with melanogenesis, the process of melanin production. These compounds work through various mechanisms, including inhibiting tyrosinase activity, suppressing MITF expression, and affecting melanosome transfer. The review highlights the potential of these compounds as safer alternatives to traditional skin-whitening agents but acknowledges the need for more in vivo research.