P-2352. Post-pandemic SARS-CoV-2 vaccination and infection status and risk of influenza-like illnesses and work absenteeism in healthcare workers a prospective cohort study

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Paper Summary

Conflicts of Interest

Identified Weaknesses

Rating Explanation

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Paper Summary

Paperzilla title

More COVID Jabs Didn't Stop Flu-Like Illnesses in Healthcare Workers

In a study of healthcare workers, increasing the number of COVID-19 vaccinations did not lead to fewer influenza-like illnesses (ILI) or days off work. Smoking and male sex were linked to more ILI, while the seasonal flu vaccine was linked to a lower risk.

Possible Conflicts of Interest

Tala Ballouz disclosed receiving grant/research support from Moderna.

Identified Weaknesses

Study Population Limited to Healthcare Workers

This limits the generalizability of findings to the general population or other specific populations. Healthcare workers may have different exposure risks, vaccination patterns, and access to healthcare compared to other groups.

ILI Assessment Based on Self-Reported Symptoms

ILI is based on self-reported symptoms, which can be subjective and prone to recall bias.

Rating Explanation

This is an observational study with a specific focus on healthcare workers, which limits its generalizability. While it employs appropriate statistical methods, the reliance on self-reported symptoms introduces a potential source of bias. One author disclosed financial ties to Moderna.

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Topic Hierarchy

Domain:

Health Sciences

Field:

Medicine

Subfield:

Public Health, Environmental and Occupational Health

File Information

Original Title:

P-2352. Post-pandemic SARS-CoV-2 vaccination and infection status and risk of influenza-like illnesses and work absenteeism in healthcare workers a prospective cohort study

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August 11, 2025 at 10:40 AM

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