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Machine learning can predict survival of patients with heart failure from serum creatinine and ejection fraction alone

★ ★ ★ ★ ☆

Paper Summary

Paperzilla title
Two Blood Tests Are All You Need to Predict Heart Failure Survival (Probably)

This study found that machine learning models, trained on only serum creatinine and ejection fraction, can accurately predict the survival of heart failure patients. These two factors alone outperformed models using all available clinical features, highlighting their potential importance in clinical practice.

Explain Like I'm Five

Scientists found that a smart computer can guess if people with a sick heart will live longer just by knowing two special numbers from their body. This works even better than using lots of other information!

Possible Conflicts of Interest

None identified

Identified Limitations

Small dataset size
The dataset employed is small (299 patients). A larger dataset would have led to more robust and reliable results.
Lack of detailed patient information
The dataset lacks additional information about patients' physical features and occupational history, potentially limiting the identification of further relevant risk factors.
No external validation set
The study lacks an external validation set from a different geographic region, which limits the ability to thoroughly assess the generalizability of the findings.

Rating Explanation

The study uses a rigorous methodology, applying diverse machine learning techniques to a real-world medical dataset. Cross-validation and exploration of feature importance strengthen the findings. The limitations around dataset size and lack of broader validation prevent a 5-star rating.

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Topic Hierarchy

Domain: Health Sciences

File Information

Original Title: Machine learning can predict survival of patients with heart failure from serum creatinine and ejection fraction alone
Uploaded: July 14, 2025 at 11:19 AM
Privacy: Public