Current evidence on gastrointestinal dysfunction in critically ill patients is limited, partly due to inconsistent definitions and monitoring tools. This review proposes a research agenda focused on priority areas like diarrhoea and feeding intolerance, highlighting the need for consensus on key definitions and standardized outcomes to improve future research.

Some authors disclosed relationships with pharmaceutical/nutritional companies; the funding sources for this research were not disclosed.

This comprehensive review provides valuable insights into GI dysfunction in critically ill patients. It systematically identifies knowledge gaps, develops future research proposals, and highlights consensus-needed areas. While the review emphasizes feasibility over high-cost studies, the extensive involvement of field experts and the overall methodological rigor make it a valuable contribution. However, limitations such as the English-language focus and the specific clinical viewpoint should be noted, warranting a score of 4.