The sample size is small (54 patients), limiting the generalizability of the findings.
The study lacks a control group, making it difficult to isolate the effects of TCM treatment.
Limited explanation of statistical analysis
The authors mention the use of multiple linear regression, but do not fully explain the model or its limitations. The reported R-squared value is moderate, indicating that the model doesn't explain a large portion of the variance in hospital stay.
Limited generalizability due to single hospital setting
The study focuses on patients in a single hospital in Wuhan, which may not represent the broader population of NCP patients.
Observational study design
The study relies on observational data, making it difficult to establish causal relationships between TCM treatment and patient outcomes.
Lack of validation of Network pharmacology
Network pharmacology component lacks validation. While interesting, it doesn't strengthen the clinical aspect due to relying solely on bioinformatic analysis.