The global burden of atopic dermatitis: lessons from the GBD Study - 1990 to 2017
Overview
Paper Summary
Atopic dermatitis ranks 15th among non-fatal diseases globally and is the leading skin disease burden worldwide based on disability-adjusted life years (DALYs). While global DALY rates for AD remained stable from 1990-2017, prevalence is highest in early childhood with a second peak in middle age, suggesting potential shifts in disease presentation across the lifespan.
Explain Like I'm Five
Scientists found that a skin itch called eczema is a really common problem around the world, making many kids and grown-ups feel uncomfortable. It's the top skin issue that makes people feel bad, especially when they are little or older.
Possible Conflicts of Interest
CF is a chief investigator in several AD-related clinical trials and research projects, and his department has received funding from Sanofi-Genzyme. RD served as a medical consultant to Altus Labs and directs a research fellowship funded by Pfizer Pharmaceuticals. While these are disclosed, they represent potential conflicts of interest.
Identified Limitations
Rating Explanation
This study provides valuable insights into the global burden of AD using a large-scale dataset. However, the reliance on secondary data and the limitations of the GBD methodology warrant a slightly lower rating. The disclosed conflicts of interest also factor into the rating.
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