Diagnosis and management of hyperprolactinemia
Overview
Paper Summary
Hyperprolactinemia, an excess of prolactin hormone, can have various causes including medication use, hypothyroidism, and pituitary disorders. Diagnosis involves excluding secondary causes and imaging the pituitary gland; treatment aims to restore hormone balance and fertility, with dopamine agonists as the first-line medical therapy and surgery reserved for specific cases.
Explain Like I'm Five
Scientists found that sometimes people have too much of a body signal called prolactin. This can happen from medicines or a tiny part of the brain not working right, but doctors can give special medicine or do surgery to make it normal again.
Possible Conflicts of Interest
The authors received an unrestricted educational grant from Paladin Labs Inc.
Identified Limitations
Rating Explanation
This is a well-written and informative review that provides valuable clinical guidance on hyperprolactinemia. It covers a wide range of relevant topics, including epidemiology, pathophysiology, diagnosis, and management. Although it lacks novel research findings and could benefit from a more critical evaluation of newer strategies, the clear and comprehensive presentation of information makes it a useful resource for healthcare professionals. The disclosed conflict of interest is noted but doesn't appear to significantly bias the content. It is slightly downgraded from a 5 due to the noted limitations.
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