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Health Sciences › Medicine › Hepatology
CDC Recommendations for Hepatitis C Screening Among Adults — United States, 2020
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Paper Summary
Conflicts of Interest
Identified Weaknesses
Rating Explanation
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Paper Summary
Paperzilla title
Everyone Gets a Hep C Test (Almost)!
The CDC recommends universal hepatitis C screening at least once for all adults and during each pregnancy, except in settings where prevalence is <0.1%. This update expands previous recommendations and aims to increase identification and treatment of hepatitis C infections, a major cause of morbidity and mortality.
Possible Conflicts of Interest
All authors have completed and submitted the International Committee of Medical Journal Editors form for disclosure of potential conflicts of interest. No potential conflicts of interest were disclosed.
Identified Weaknesses
Heterogeneity and limitations of included studies
The literature reviews are subject to limitations such as heterogeneity of individual study results, limitations of included studies (e.g., recall bias, low response rates), and potential publication bias. These factors can affect the comparability and generalizability of the findings.
Limited generalizability
Studies performed in high-burden areas might not be representative of the general population, which could limit the external validity of the systematic review.
Potential publication bias
Publication bias might favor studies reporting high disease prevalence, potentially impacting the external validity of the review.
Rating Explanation
This paper presents updated recommendations for hepatitis C screening based on comprehensive systematic reviews and cost-effectiveness analyses. The recommendations for universal screening in adults and pregnant women are well-supported and address a significant public health issue. The methodology is sound, although the literature reviews have some limitations. Overall, this is a strong and important contribution to public health.
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File Information
Original Title:
CDC Recommendations for Hepatitis C Screening Among Adults — United States, 2020
File Name:
rr6902a1-H.pdf
[download]
File Size:
0.38 MB
Uploaded:
July 14, 2025 at 10:45 AM
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