Immunomodulatory effect of mushrooms and their bioactive compounds in cancer: A comprehensive review
Overview
Paper Summary
This review suggests that mushrooms might have potential as anti-cancer agents, impacting immune cells and inhibiting tumor growth based primarily on preclinical studies. More clinical trials are needed to determine if mushroom supplements are actually effective for cancer treatment in humans. The standardization and quality control of mushroom products is also a concern.
Explain Like I'm Five
Scientists found that some mushrooms might help your body's "good guy" cells fight bad cancer cells and stop them from growing. But we need more tests to be sure they work for people.
Possible Conflicts of Interest
None identified
Identified Limitations
Rating Explanation
This review summarizes preclinical and some clinical evidence suggesting that mushrooms and their compounds have immunomodulatory and anti-cancer effects. However, clinical evidence is still limited, and more high-quality human trials are needed to validate these findings. The review relies on in vitro and in vivo studies, which may not translate to clinical efficacy in humans. While the review highlights the potential of mushrooms as adjunctive therapy, it doesn't fully address the potential risks and drug interactions.
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