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Burden of anemia and its underlying causes in 204 countries and territories, 1990–2019: results from the Global Burden of Disease Study 2019
Paper Summary
Paperzilla title
Anemia: Still a Global Pain, But Getting Better (Mostly)
Anemia affects around 1.8 billion people globally and caused 50.3 million years lived with disability (YLDs) in 2019. While age-standardized rates of anemia have decreased since 1990, the absolute numbers have increased, likely due to population growth and aging. Dietary iron deficiency remains the primary cause of anemia worldwide.
Possible Conflicts of Interest
The GBD study is funded by the Bill and Melinda Gates Foundation. While the authors state the foundation was not involved in manuscript preparation, the funding source should be noted. Additional funding for this specific report was provided by Shahid Beheshti University of Medical Sciences.
Identified Weaknesses
Data Sparsity and Accuracy
The study relies on data from the Global Burden of Disease (GBD) study, which may have limitations in data availability and accuracy, especially in less developed countries. This could affect the precision of the estimated burden of anemia.
Lack of Specificity by Anemia Type
The study does not report the burden of anemia by specific type (e.g., iron deficiency anemia, sickle cell anemia). This limits the ability to provide targeted preventative recommendations.
Missing Data on Risk Factors
The study lacks data on some potential risk factors for anemia, grouped as "other neglected tropical diseases" and "other unspecified infectious diseases." This hinders a complete understanding of the factors associated with anemia.
Rating Explanation
This study provides a valuable update on the global burden of anemia using the most recent GBD data. While there are limitations related to data sparsity and the lack of specific anemia type analysis, the overall methodology is robust, and the findings have important implications for public health policy.
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File Information
Original Title:
Burden of anemia and its underlying causes in 204 countries and territories, 1990–2019: results from the Global Burden of Disease Study 2019
Uploaded:
July 14, 2025 at 10:54 AM
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