COVID-19 Excess Deaths in Peru's 25 States in 2020: Nationwide Trends, Confounding Factors, and Correlations With the Extent of Ivermectin Treatment by State
Overview
Paper Summary
This ecological study found a correlation between ivermectin use and decreased excess deaths in Peru during the 2020 COVID-19 pandemic. However, confounding factors like differing public health measures, population demographics, and the timing of interventions across regions could not be fully controlled. Therefore, the study's results do not confirm a causal relationship between ivermectin and reduced mortality.
Explain Like I'm Five
A study in Peru showed a link between ivermectin use and fewer COVID deaths, but there are other factors that could explain this, and more research is needed.
Possible Conflicts of Interest
Two authors (Hibberd and Chamie-Quintero) have affiliations with organizations that actively promote the use of ivermectin for COVID-19. Chamie-Quintero also received payments from an ivermectin advocacy group.
Identified Limitations
Rating Explanation
The study presents an interesting correlation, but the ecological design and uncontrolled confounding factors limit the strength of the conclusions. The authors' affiliations with pro-ivermectin organizations also raise concerns about potential bias.
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