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Sensory Systems

Sensory Systems

Neural processing of sensory information, including vision, hearing, touch, taste, smell, pain perception, and the development of sensory prosthetics and interfaces

5 papers in this specialization

Paperzilla Papers in Sensory Systems

Network synchrony creates neural filters promoting quiescence in Drosophila

This study in fruit flies shows that rhythmic, slow-wave brain activity (SWA) between specific neural networks acts as a filter for sensory information, allowing the flies to enter a quiet state similar to rest or light sleep. The filter can be 'broken' by stronger stimuli, like a puff of air, triggering a response. The research provides a detailed model of how these networks interact, with one network overriding another to control sensory processing and behavior.

Aug 23, 04:13 PM

SARS-CoV-2 is associated with changes in brain structure in UK Biobank

This longitudinal study found that SARS-CoV-2 infection is associated with changes in brain structure, primarily in regions connected to the olfactory system, and cognitive decline. These effects were observed even in mild cases and persisted after excluding hospitalized patients, suggesting a potential long-term impact of COVID-19 on brain health.

s41586-022-04569-5.pdf

Jul 14, 11:12 AM

The native ORAI channel trio underlies the diversity of Ca2+ signaling events

This study demonstrates that ORAI2 and ORAI3, often overshadowed by ORAI1, play critical roles in generating regenerative Ca2+ oscillations and fine-tuning receptor-activated Ca2+ signals. These findings suggest that the native CRAC channel functions as a heteromultimer of ORAI isoforms, broadening the sensitivity of cells to diverse agonist concentrations and enabling differential activation of NFAT transcription factors.

s41467-020-16232-6.pdf

Jul 14, 11:12 AM

Tinnitus prevalence in Europe: a multi-country cross-sectional population study

The study found that 14.7% of adults in 12 EU countries experience tinnitus, with prevalence ranging from 8.7% in Ireland to 28.3% in Bulgaria. Tinnitus prevalence increased with age and hearing difficulty, and varied significantly between countries, with higher rates observed in Eastern European countries with lower GDP.

1-s2.0-S2666776221002362-main.pdf

Jul 14, 11:12 AM

Characterization of the development of the mouse cochlear epithelium at the single cell level

This study identifies a distinct lateral prosensory population in the developing mouse cochlea that gives rise to outer hair cells and surrounding support cells. The researchers characterize the transcriptional changes during outer hair cell development and demonstrate that Tgfbr1 activity is required for this process.

s41467-020-16113-y.pdf

Jul 14, 11:12 AM

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