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Neurology
Neurology
Clinical neuroscience and neurological disorders, including neurodegeneration, neuroimmunology, neuromuscular diseases, and translational approaches to neurological treatment
3 papers in this specialization
Papers
Identification of region-specific astrocyte subtypes at single cell resolution
This study identifies five distinct astrocyte subtypes in the adult mouse cortex and hippocampus using single-cell RNA sequencing. These subtypes exhibit unique molecular signatures, distinct spatial positioning, and specialized morphologies and Ca2+ signaling properties, suggesting functional diversity within and between brain regions.
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s41467-019-14198-8.pdf
Jul 14, 11:00 AM
Overview of General and Discriminating Markers of Differential Microglia Phenotypes
This review gathers, classifies, and describes known and recently discovered protein markers expressed by microglial cells in their different phenotypes. It aims to provide a comprehensive and practical guide for choosing proper, more specific markers for detailed studies on microglia and neuroinflammatory mechanisms in various physiological as well as pathological conditions.
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pdf.pdf
Jul 14, 11:00 AM
Modular output circuits of the fastigial nucleus mediate diverse motor and nonmotor functions of the cerebellar vermis
The study identified five major types of glutamatergic projection neurons in the mouse fastigial nucleus (cerebellar vermis) with distinct gene expression, morphology, and connectivity patterns. These cell types form modular circuits with specific Purkinje cells and inferior olive neurons and project to distinct downstream targets in the brainstem, thalamus, and forebrain, suggesting their involvement in a wide range of motor and nonmotor functions, including posture, locomotion, oromotor control, orienting, arousal, and cognition.
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2020.04.23.047100.full.pdf
Jul 14, 11:00 AM
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