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ADHD Diagnosis and Timing of Medication Initiation Among Children Aged 3 to 5 Years

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Paper Summary

Paperzilla title
ADHD Meds for Preschoolers: Skipping Behavioral Therapy?

This study found that a substantial proportion of preschoolers diagnosed with ADHD started medication within 30 days, often before behavioral therapy was attempted. Racial and insurance disparities were evident, with White children and those with public insurance more likely to receive early medication. Follow-up rates after medication initiation appeared low, but likely underestimated due to limitations in data capture.

Explain Like I'm Five

In a study of kids 3-5 years old, many were given ADHD meds soon after diagnosis, even though guidelines recommend trying behavioral therapy first. This was especially true for White kids and those with public insurance.

Possible Conflicts of Interest

Dr. Brink reported receiving grants from Nationwide Children's Hospital during the study. Dr. Harris reported receiving research support from lonis Pharmaceuticals, Grace Science Foundation, and Lou Foundation; personal fees for consulting from Shionogi, Inc, and Key Quest Health; and honoraria from UpToDate outside the submitted work. Dr. Wallis reported being a paid consultant to Healthy Steps and Thomas Jefferson University and serving as an expert witness for Kline Spector, LLC.

Identified Limitations

Reliance on diagnostic codes
The study relies on diagnostic codes, which can be inaccurate, and doesn't capture the nuanced reasons behind medication decisions, like unavailable behavioral therapy or parent preferences.
Underestimation of follow-up rates
The study doesn't fully capture follow-up rates because it misses data from phone calls, secure messaging, or subspecialist referrals.
Lack of information on behavioral treatment recommendations
Information on PCP recommendations for first-line behavioral treatment and reasons for prescribing nonstimulant medications was not available.

Rating Explanation

This is a multi-site retrospective study using a large sample size providing valuable insights into real-world ADHD management in preschoolers. However, its reliance on diagnostic codes, potential underestimation of follow-up rates, and lack of information on PCP recommendations for behavioral treatment limit the strength of the conclusions. The disclosed conflicts of interest also warrant consideration.

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Topic Hierarchy

Domain: Health Sciences
Field: Medicine

File Information

Original Title: ADHD Diagnosis and Timing of Medication Initiation Among Children Aged 3 to 5 Years
Uploaded: September 01, 2025 at 01:12 PM
Privacy: Public