Preventing Kidney Injury in Critical Care: A Review of Strategies

Overview

Paper Summary › Explain Like I'm Five › Conflicts of Interest › Identified Limitations › Rating Explanation › Good to know › Topic Hierarchy › File Information ›

Paper Summary

Paperzilla title

This narrative review discusses strategies for preventing acute kidney injury (AKI) in critically ill patients, including biomarkers for early diagnosis, discussion of AKI-CKD transition, and the selection of appropriate endpoints for prevention trials. The review highlights the importance of prevention due to AKI's impact on short- and long-term outcomes and emphasizes implementing proven strategies in clinical practice.

Explain Like I'm Five

Acute kidney injury (AKI) is a serious condition for the critically ill. This review looks at how we can better detect and prevent AKI to improve patient outcomes.

Possible Conflicts of Interest

Some authors declared financial ties to pharmaceutical and medical device companies related to AKI diagnosis and treatment.

Identified Limitations

Narrative review

Narrative reviews lack the systematic and rigorous methodology of other review types like systematic reviews and meta-analyses. This can lead to selection bias and potentially skewed representations of the evidence base.

Limited scope

The review focuses primarily on AKI prevention in cardiac surgery patients, limiting the generalizability of its findings to other clinical settings and AKI etiologies.

Lack of in-depth discussion on management and RRT

Excluding a discussion on AKI management and renal replacement therapy provides an incomplete picture of AKI care for critically ill patients.

Rating Explanation

This is a comprehensive review on a clinically significant topic, summarizing valuable information on AKI prevention strategies. However, the limitations inherent to its narrative nature and specific focus on cardiac surgery warrant a rating of 4 rather than 5.

Good to know

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Topic Hierarchy

Domain: Health Sciences

Field: Medicine

Subfield: Critical Care and Intensive Care Medicine

File Information

Original Title: Preventing acute kidney injury and its longer-term impact in the critically ill

Uploaded: September 20, 2025 at 05:18 PM

Privacy: Public