Paper Summary
Paperzilla title
Watch Your Weight Before and During Pregnancy for a Healthier Baby!
The study found that being overweight or obese before pregnancy and gaining excessive weight during pregnancy are linked to increased risks of gestational diabetes, gestational hypertension, having a large baby, and delivering a baby that is large for gestational age. Conversely, insufficient weight gain was associated with gestational diabetes and low birth weight.
Possible Conflicts of Interest
The study received funding from the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences, but it is stated that the funder had no role in the study design, data collection, analysis, interpretation, or manuscript writing.
Identified Weaknesses
Limited Sample Size for Stratification
The sample size, while large, may not be sufficient for robust stratification based on factors like age, potentially limiting the power of the analysis.
Potential Bias in Pre-pregnancy BMI Measurement
The pre-pregnancy weight and height data, collected during the initial prenatal examination, are subject to potential bias as they do not represent true pre-pregnancy measurements.
Inter-institutional Variability in Measurement Protocols
Variations in measurement protocols across different study institutions may introduce inconsistencies and bias in BMI classifications.
Lack of Control for Confounding Factors
The study lacks detailed information about potential confounding factors like clinical complications or lifestyle changes during pregnancy, which could influence the outcomes.
Rating Explanation
This is an average study with a relevant research question and a large sample size. However, several methodological limitations, such as potential bias in pre-pregnancy BMI measurement and lack of control for confounding factors, prevent it from receiving a higher rating.
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File Information
Original Title:
Effects of pre-pregnancy body mass index and gestational weight gain on maternal and infant complications
Uploaded:
July 14, 2025 at 10:47 AM
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