Low-Risk Differentiated Thyroid Cancer and Radioiodine Remnant Ablation: A Systematic Review of the Literature
Overview
Paper Summary
A review of studies found no evidence that radioactive iodine treatment after surgery benefits low-risk differentiated thyroid cancer patients. The results for intermediate-risk patients are mixed, with some studies suggesting a benefit and others showing no effect. This highlights the need for better quality evidence, such as from randomized controlled trials, to guide decisions about radioactive iodine treatment in these patients.
Explain Like I'm Five
This study suggests that using radioactive iodine after thyroid cancer surgery to destroy leftover thyroid tissue may not benefit low-risk or certain intermediate-risk patients.
Possible Conflicts of Interest
None identified
Identified Limitations
Rating Explanation
This is a systematic review which summarizes existing literature, which is useful for clinical decision making. However, it relies on observational studies, which are prone to biases, and didn't address quality of life. Additionally, the evidence for intermediate-risk patients is not definitive.
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