The Common Cold Is Associated With Protection From SARS-CoV-2 Infections
Overview
Paper Summary
This study found that recent rhinovirus infections are linked to a lower risk of SARS-CoV-2 infection and reduced viral loads in those infected. Children experience more rhinovirus infections and express higher levels of certain antiviral genes, which may partially explain why they generally have milder COVID-19 cases. More research is needed to establish causality and understand the underlying mechanisms fully.
Explain Like I'm Five
Kids catch colds more often than adults, and this may boost their immune systems against COVID-19 by turning on special genes that fight off the virus.
Possible Conflicts of Interest
Several authors disclosed financial ties to pharmaceutical companies.
Identified Limitations
Rating Explanation
This study provides compelling evidence for the protective effect of rhinovirus infections against SARS-CoV-2, suggesting a potential mechanism. However, the correlational nature of the study warrants a slightly lower rating. The disclosed conflicts of interest are noted but do not appear to significantly impact the study's validity.
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