PAPERZILLA
Crunching Academic Papers into Bite-sized Insights.
About
Sign Out
← Back to papers
Health Sciences › Medicine › Family Practice
Medication adherence and its determinants in patients after myocardial infarction
★
★
★
☆
☆
SHARE
Overview
Paper Summary
Conflicts of Interest
Identified Weaknesses
Rating Explanation
Good to know
Topic Hierarchy
File Information
Paper Summary
Paperzilla title
Pills and Thrills: Post-MI Med Adherence Dwindles Over Time (But Married Folks Do Better!)
Medication adherence after myocardial infarction decreases over time for ACE inhibitors, P2Y12 inhibitors, and statins. Several sociodemographic (age, employment, education, marital status, location, economic status) and clinical factors (prior CABG) influence adherence levels, with married and younger patients tending to have better adherence.
Possible Conflicts of Interest
This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors. The authors declare no competing interests.
Identified Weaknesses
Indirect measure of adherence
The study relies on filled prescription data as a proxy for medication adherence, which may not accurately reflect actual medication intake. Patients may fill prescriptions but not take the medications as prescribed.
Limited scope of medication assessment
The study does not account for over-the-counter medications or non-pharmacological interventions that patients may be using, which could influence adherence to prescribed medications.
Limited generalizability
The study population is limited to patients receiving reimbursed medications, which may not be representative of the broader post-MI population. This limits the generalizability of the findings.
Single-center design
The study uses a single-center design, which may introduce bias and limit the generalizability of the findings to other settings.
Small sample size
The study has a relatively small sample size, which may limit the statistical power of the analyses and the ability to detect small but potentially important effects.
Rating Explanation
This is an average observational study with a relevant clinical question. The findings regarding declining adherence and associated factors are important, but several methodological limitations (indirect adherence measure, limited scope of medication assessment, limited generalizability due to single-center design and reimbursed medication focus, small sample size) prevent a higher rating. No overt conflicts of interest were identified.
Good to know
This is our free standard analysis. Paperzilla Pro fact-checks every citation, researches author backgrounds and funding sources, and uses advanced AI reasoning for more thorough insights.
Explore Pro →
Topic Hierarchy
File Information
Original Title:
Medication adherence and its determinants in patients after myocardial infarction
File Name:
s41598-020-68915-1.pdf
[download]
File Size:
1.12 MB
Uploaded:
July 14, 2025 at 11:27 AM
Privacy:
🌐 Public
© 2025 Paperzilla. All rights reserved.