Paper Summary
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Integrative Medicine for Cancer Pain: Some Relief, But More Research Needed!
Acupuncture is recommended for aromatase inhibitor-related joint pain. Acupuncture, reflexology, acupressure, and massage may be offered for other types of cancer pain, particularly in palliative care. Evidence for other integrative therapies and natural products for cancer pain is currently inconclusive, warranting further research.
Possible Conflicts of Interest
All members of the Expert Panel completed disclosure forms, and the majority did not disclose any relationships constituting a conflict of interest. However, some panel members did report financial ties to pharmaceutical companies, which could be considered a potential conflict of interest, although these were deemed not to influence the recommendations.
Identified Weaknesses
Many of the reviewed studies had small sample sizes, limiting the statistical power and generalizability of the findings.
The studies used various outcome measures, interventions, and control groups, making it challenging to compare results and draw definitive conclusions.
Methodological Limitations
Several studies lacked adequate blinding or had high attrition rates, potentially introducing bias and reducing the reliability of the results.
Limited Methodological Rigor
For many integrative interventions, trials are small and are often limited by a lack of methodological rigor.
Exclusion of Non-Randomized Studies
The guideline methodology excluded non-randomized pragmatic studies, which may be more reflective of real-life integrative oncology practice.
Rating Explanation
This guideline provides a valuable overview of integrative medicine interventions for cancer pain, highlighting some promising therapies like acupuncture and massage. However, the evidence base for many interventions is limited by small sample sizes, methodological flaws, and heterogeneity of studies. The rating reflects these limitations and the need for further research.
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File Information
Original Title:
Integrative Medicine for Pain Management in Oncology: Society for Integrative Oncology-ASCO Guideline
Uploaded:
July 14, 2025 at 10:54 AM
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