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Health Sciences › Medicine › Psychiatry and Mental health
Association of time spent in outdoor light and genetic risk with the incidence of depression
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Paper Summary
Conflicts of Interest
Identified Weaknesses
Rating Explanation
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Paper Summary
Paperzilla title
Soaking Up the Sun: Optimal Outdoor Light Linked to Lower Depression Risk, Even for Those Genetically Predisposed
This study found a non-linear relationship between time spent in outdoor light and depression risk, with an average of 1.5 hours per day associated with the lowest risk. Genetic predisposition to depression increased risk, but this could be mitigated by spending the optimal amount of time outdoors. The study was limited to white participants in the UK Biobank.
Possible Conflicts of Interest
None identified
Identified Weaknesses
Self-reported data
The study relies on self-reported time spent in outdoor light, which can be subject to recall bias and inaccuracies.
Limited generalizability
The study population is limited to white participants from the UK Biobank, which limits the generalizability of the findings to other ethnicities and populations.
Underestimation of depression incidence
The study only considers hospital admission records for depression, which may underestimate the true incidence of depression in the population.
Uncontrolled confounders
The study does not account for all potential confounding factors, such as workload, job details, and the intensity and temperature of outdoor light, which may influence the relationship between time spent outdoors and depression risk.
Rating Explanation
This is a large, prospective cohort study with a robust methodology. While some limitations exist, the findings are valuable and contribute to our understanding of the relationship between outdoor light, genetic predisposition, and depression risk.
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File Information
Original Title:
Association of time spent in outdoor light and genetic risk with the incidence of depression
File Name:
s41398-023-02338-0.pdf
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File Size:
1.14 MB
Uploaded:
July 21, 2025 at 06:34 AM
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