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Health SciencesMedicineReproductive Medicine

ART in Europe, 2017: results generated from European registries by ESHRE
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Paper Summary
Conflicts of Interest
Identified Weaknesses
Rating Explanation
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Paper Summary
Paperzilla title
European ART in 2017: More IVF, Less Twins, and a Frozen Embryo Boom!
This study analyzes data on Assisted Reproductive Technology (ART) in Europe from 2017, showing a continuing trend towards increased use of ICSI and frozen embryo replacement. The proportion of single embryo transfers continued to rise, leading to a further decrease in multiple birth rates.
Possible Conflicts of Interest
The study was funded by ESHRE (European Society of Human Reproduction and Embryology). While the authors declare no competing interests, the funding source's role in the research and potential influence on results should be considered.
Identified Weaknesses
Variability in Data Collection and Reporting
The heterogeneity in data collection methods and reporting levels across different European countries makes it challenging to draw definitive conclusions and compare results directly. Variations in definitions, practices (like freeze-all cycles), and data completeness can lead to skewed interpretations.
Missing Data
The study acknowledges that some countries were unable to provide data on initiated cycles and deliveries. This missing data can impact the accuracy of overall estimations and comparisons between countries.
Incomplete Cross-Border Data
While the study presents data on cross-border reproductive care, the information regarding patients' countries of origin is incomplete and unreliable. This limits the ability to fully understand the extent and reasons for cross-border treatment.
Aggregated Data
The reliance on aggregated data prevents the calculation of true cumulative delivery and live birth rates. While a proxy-indicator is used, it is not a perfect representation and can affect the interpretation of treatment effectiveness.
Limited Analysis of FER Variations
The study observes variations in the proportion of frozen embryo replacement (FER) cycles among countries and suggests this reflects different practices. However, it doesn't delve deeper into the reasons behind these variations or their specific impact on outcomes.
Rating Explanation
This study provides a valuable overview of ART, IUI, and FP trends in Europe using data from a large number of countries and clinics. The analysis of trends in treatment cycles, multiple births, and embryo transfer practices is insightful. However, several limitations regarding data completeness, variability in collection methods, and reliance on aggregated data prevent a higher rating.
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Topic Hierarchy
File Information
Original Title:
ART in Europe, 2017: results generated from European registries by ESHRE
File Name:
ART_in_Europe_2017_results_generated_from_European_registries_by_ESHRE_2021.pdf
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File Size:
0.63 MB
Uploaded:
July 14, 2025 at 10:51 AM
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