Paper Summary
Paperzilla title
From NAFLD to MASLD: A New Name for Fatty Liver Disease
The study proposes replacing "NAFLD" with "MASLD" (metabolic dysfunction-associated steatotic liver disease), reflecting the central role of metabolic dysfunction. It also proposes diagnostic criteria based on the presence of at least one cardiometabolic risk factor and creates a separate category ("MetALD") for patients with MASLD and increased alcohol consumption.
Possible Conflicts of Interest
Many authors disclosed consulting relationships with or receiving grants from pharmaceutical companies involved in NAFLD research and treatment.
Identified Weaknesses
Potential bias in the Delphi panel
The Delphi method, while useful for gathering expert opinions, can be susceptible to bias and may not fully capture the diversity of perspectives on a complex issue like NAFLD nomenclature.
Rating Explanation
This study used a robust, multi-stage Delphi process with a diverse panel of experts and patient advocates to reach consensus on new nomenclature for fatty liver disease. The thorough methodology, global representation, and inclusion of patient perspectives are strengths. However, potential bias in the Delphi method and the declared COIs of some authors slightly lower the rating.
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File Information
Original Title:
A multisociety Delphi consensus statement on new fatty liver disease nomenclature
File Name:
a_multisociety_delphi_consensus_statement_on_new.28.pdf
Uploaded:
July 14, 2025 at 06:48 AM
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