A portrait of the infected cell: how SARS-CoV-2 infection reshapes cellular processes and pathways
Descripción general
Resumen del artículo
This review examines how SARS-CoV-2 alters cellular pathways, particularly those related to the ER, autophagy, and lipid metabolism. The virus manipulates these pathways to create a favorable environment for replication, including the formation of replication organelles and evasion of host defenses. Further research is needed to fully understand the complex interplay between the virus and host and its impact on disease pathogenesis.
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SARS-CoV-2 infection significantly impacts cellular processes and pathways, particularly those related to the endoplasmic reticulum (ER), autophagy, and lipid metabolism, to promote its replication and spread within the host.
Posibles conflictos de intereses
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Limitaciones identificadas
Explicación de la calificación
This review provides a strong overview of key cellular processes hijacked by SARS-CoV-2, using valid scientific evidence from various published studies. While relying heavily on in vitro data, the review effectively synthesizes current knowledge and highlights crucial areas for future research.
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