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Gene name errors: Lessons not learned

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Resumen del artículo

Título de Paperzilla
Gene Name Errors in Spreadsheets: Still a Thing!

This study found that gene name errors in supplementary Excel files continue to be a problem in genomics research, with a higher prevalence (30.9%) than previously reported. The errors are often due to automatic conversion of gene names into dates or other data formats, which is particularly prevalent in Microsoft Excel and Google Sheets. Five-digit numbers (internal date format) represent a new major source of errors, contributing to the discrepancy from past reports.

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Scientists found that their computer lists sometimes mess up important gene names by changing them into dates or numbers by mistake. It's like your toy's name sticker turning into a random date, making it hard to know what's inside!

Posibles conflictos de intereses

None identified

Limitaciones identificadas

Limited Scope of Analysis
The study focuses on open-access articles in PubMed Central and those with the keyword "genom*" in the title or abstract, limiting the generalizability of the findings to all published scientific literature.
Potential for Missed Errors
While manual verification of suspected errors was performed, there remains a possibility that some errors were missed, particularly those in horizontal lists or with non-standard formats.
Lack of Impact Assessment
The study identifies the prevalence of gene name errors but doesn't deeply investigate the downstream consequences of these errors on research conclusions. Further research is needed to quantify the real-world impact.

Explicación de la calificación

This study provides valuable insights into the persistent problem of gene name errors in supplementary data files and highlights the need for improved research practices. The updated screening method and extensive analysis of PubMed Central articles strengthen the findings. While some limitations exist regarding the scope and impact assessment, the overall methodology is sound and the findings are relevant to improving the quality of published research.

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Jerarquía temática

Subcampo: Software

Información del archivo

Título original: Gene name errors: Lessons not learned
Subido: 14 jul 2025, 11:22:30
Privacidad: Público