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Immunomodulatory effect of mushrooms and their bioactive compounds in cancer: A comprehensive review

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Resumen del artículo

Título de Paperzilla
Mushrooms vs. Cancer: Promising Preclinical Data, But Need More Human Trials!

This review suggests that mushrooms might have potential as anti-cancer agents, impacting immune cells and inhibiting tumor growth based primarily on preclinical studies. More clinical trials are needed to determine if mushroom supplements are actually effective for cancer treatment in humans. The standardization and quality control of mushroom products is also a concern.

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Scientists found that some mushrooms might help your body's "good guy" cells fight bad cancer cells and stop them from growing. But we need more tests to be sure they work for people.

Posibles conflictos de intereses

None identified

Limitaciones identificadas

Limited clinical evidence
The review focuses on preclinical and some clinical studies which are not enough to support the generalized use of mushrooms for cancer treatment.
Reliance on traditional use and preclinical data
Traditional use and preclinical data do not guarantee clinical efficacy.
Lack of standardization and quality control of mushroom products
The review acknowledges the lack of standardization and quality control in mushroom products, which raises concerns about their efficacy and safety.
Limited discussion of side effects and drug interactions
The review does not comprehensively discuss the potential side effects and drug interactions of mushrooms, which is crucial for clinical application.

Explicación de la calificación

This review summarizes preclinical and some clinical evidence suggesting that mushrooms and their compounds have immunomodulatory and anti-cancer effects. However, clinical evidence is still limited, and more high-quality human trials are needed to validate these findings. The review relies on in vitro and in vivo studies, which may not translate to clinical efficacy in humans. While the review highlights the potential of mushrooms as adjunctive therapy, it doesn't fully address the potential risks and drug interactions.

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Jerarquía temática

Campo: Medicina

Información del archivo

Título original: Immunomodulatory effect of mushrooms and their bioactive compounds in cancer: A comprehensive review
Subido: 19 jul 2025, 18:45:04
Privacidad: Público